deferasirox

Definition / meaning of deferasirox

A synthetic, orally bioavailable, achiral, tridentate triazole derived from salicylic acid with iron-chelating activity. Deferasirox chelates iron at a 2:1 (ligand:iron) ratio. Because of its oral availablity,and long plasma half-life, this agent may be superior to desferrioxamine (desferal, DFO), which is orally inactive and has a short plasma half-life.

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Find More About 'deferasirox'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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