cilengitide

Definition / meaning of cilengitide

A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.

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Find More About 'cilengitide'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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