carubicin

Definition / meaning of carubicin

An anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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