bromodeoxyuridine

Definition / meaning of bromodeoxyuridine

A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks (DSBs).

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Find More About 'bromodeoxyuridine'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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