bicalutamide

Definition / meaning of bicalutamide

A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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