bavituximab

Definition / meaning of bavituximab

An IgG3 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Chimeric anti-phosphotidylserine monoclonal antibody binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.

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Find More About 'bavituximab'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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