axitinib

Definition / meaning of axitinib

An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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