autologous Epstein-Barr virus-specific cytotoxic T lymphocytes

Definition / meaning of autologous Epstein-Barr virus-specific cytotoxic T lymphocytes

A preparation of lymphocytes harvested from a patient with an Epstein-Barr virus (EBV)-positive tumor. Ex vivo, the lymphocytes are activated against EBV-specific antigens and then returned to the patient, where they mount a specific immune response against EBV-positive tumor cells.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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