atamestane

Definition / meaning of atamestane

A synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.

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Find More About 'atamestane'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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