antibody-dependent cell-mediated cytotoxicity

Definition / meaning of antibody-dependent cell-mediated cytotoxicity

A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of white blood cells. The white blood cells bind to the antibodies and release substances that kill the target cells or microbes. Also called ADCC and antibody-dependent cellular cytotoxicity.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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