allogeneic tumor cell vaccine

Definition / meaning of allogeneic tumor cell vaccine

A vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and administered to another patient in order to stimulate cytotoxic immune responses to a similar tumor cell type. The cells found in this type of whole-cell vaccine express many cell-surface tumor-associated antigens. This vaccine is frequently administered with an adjuvant immunostimulant.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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