allogeneic dendritic cell-myeloma idiotype vaccine

Definition / meaning of allogeneic dendritic cell-myeloma idiotype vaccine

A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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