adenovector encoding MDA7

Definition / meaning of adenovector encoding MDA7

A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene (MDA7) with potential antineoplastic activity. After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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