5Q minus syndrome

Definition / meaning of 5Q minus syndrome

A rare disorder caused by loss of part of the long arm (Q arm) of human chromosome 5. This syndrome affects myeloid (bone marrow) cells, causing treatment-resistant anemia, and myelodysplastic syndromes that may lead to acute myelogenous leukemia. Also called 5Q- syndrome.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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