4′-iodo-4′-deoxydoxorubicin

Definition / meaning of 4′-iodo-4′-deoxydoxorubicin

An iodinated doxorubicin analogue with antiamyloid activity. 4′-Iodo-4′-deoxydoxorubicin (IDOX) binds with high affinity to five types of natural amyloid fibrils including immunoglobulin light chains, amyloid A, transthyretin (methionine-30 variant),

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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