transdermal

Meaning of transdermal: Transdermal describes a medication delivery method in which a drug passes through unbroken skin into the bloodstream, often using a patch.

Definition of transdermal

Transdermal describes the delivery of a substance, most often a medication, through unbroken skin and into the bloodstream. This route is commonly achieved using an adhesive patch containing the drug, which is worn on the skin and releases medication gradually over a set period of time.

Because the medication is absorbed continuously through the skin, a transdermal route can provide a steadier level of drug in the bloodstream compared with a dose taken by mouth, and it avoids the digestive breakdown a medication undergoes when swallowed. Transdermal products are used for a variety of medications, including certain pain relievers, hormone therapies, and smoking cessation aids.

The rate at which a medication is absorbed transdermally can be affected by factors such as skin thickness, temperature, and the specific formulation of the patch or product.

How transdermal is built

trans derm al transdermal
  • trans- Prefix · Latin across, through
  • cutane/o, derm/o Combining form · Latin skin
  • -ac, -al, -ar, -ary, -eal, -ic Suffix · Greek and Latin pertaining to, relating to

A medical term is read from its ending backwards: the suffix first, then the prefix, then the root. See all 223 word parts.

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Used in a sentence

The patient was switched to a transdermal patch for more consistent pain control.

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Good to know

A transdermal patch delivers medication continuously over its wearing period, which differs from an oral dose that produces a peak and decline in drug level after each administration.

Word origin

Where “transdermal” comes from

Formed from trans- (Latin, meaning "across") and dermal, from Greek derma, meaning "skin."

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.