topical

Meaning of topical: A topical medication is applied directly to the skin or another body surface to act at that location rather than throughout the body.

Definition of topical

Topical describes a medication, product, or treatment that is applied directly to a body surface, most often the skin, but also the eye, ear, or mucous membranes, to act primarily at the site of application. Common topical forms include creams, ointments, gels, patches, and drops.

Because a topical medication is intended to act locally, it generally produces a lower level of drug circulating throughout the rest of the body than the same medication given by mouth or injection, though some absorption into the bloodstream can still occur depending on the drug, the dose, and the condition of the skin or surface where it is applied.

The topical route is often chosen specifically to treat a localized problem, such as a skin infection or inflammation, while limiting exposure of the rest of the body to the medication.

Used in a sentence

A topical corticosteroid was prescribed for the localized area of inflamed skin.

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Good to know

A topical medication is not free of systemic effects; absorption through broken or extensively treated skin can still raise the amount reaching general circulation.

Word origin

Where “topical” comes from

From Greek topos, meaning "place."

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.