plasma cell
A plasma cell is a mature immune cell derived from an activated B cell that manufactures large quantities of a specific antibody.
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A plasma cell is a mature immune cell derived from an activated B cell that manufactures large quantities of a specific antibody.
Read definitionA type of cancer that begins in plasma cells (white blood cells that produce antibodies).
Read definitionA single collection of abnormal antibody-making cells, which may stay solitary or prove to be the first sign of myeloma.
Read definitionPleomorphic describes cells, tissue, or organisms that appear in varied shapes and sizes rather than in one uniform, consistent form.
Read definitionA vast family of plant compounds behind bitterness, astringency and some plant colors, and among the most studied parts of the diet.
Read definitionPolyposis is the development of numerous polyps, growths projecting from a mucous membrane, most often described within the colon.
Read definitionA cancer vaccine consisting of whole irradiated heterologous melanoma cells which express multiple melanoma-related antigens.
Read definitionPomalidomide is an approved oral treatment for multiple myeloma that alters immune activity and blood vessel formation around tumor cells.
Read definitionA folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
Read definitionMultiplying or increasing in number.
Read definitionCells that manufacture antibody by the ton depend most on clearing protein waste, which is why myeloma is unusually sensitive to the block.
Read definitionA drug used to treat multiple myeloma.
Read definitionNeither an infection nor catching, it runs in flares and quiet spells and can involve the nails and joints as well as the skin.
Read definitionA substance that is being studied for its ability to make cancer cells respond to drugs to which they have become resistant.
Read definitionNamed for the island where the soil bacterium was dug up, and the enzyme it blocks was later named after the drug.
Read definitionRecurrence describes cancer returning after treatment, either near the original tumor site or in another part of the body.
Read definitionA condition labeled refractory has not responded as expected to treatment, prompting reconsideration of the diagnosis or a change in approach.
Read definitionResting describes a cell that is temporarily inactive with respect to division, distinguishing it from one actively multiplying.
Read definitionA chemical relative of thalidomide, redeveloped for cancer and now a mainstay of treatment for multiple myeloma.
Read definitionRifampin is an antibiotic most often used as a core component of combination treatment for tuberculosis and certain other mycobacterial infections.
Read definitionFor learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.