Home/Topics/General Medical Terms/scleroderma General Medical Terms scleroderma Listen Save Share Print Meaning of scleroderma: A chronic disorder marked by hardening and thickening of the skin. Definition of scleroderma A chronic disorder marked by hardening and thickening of the skin. Scleroderma can be localized or it can affect the entire body (systemic). Written and maintained by James Murray · Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations. Keep exploringRelated termsMore in General Medical Terms → General Medical Terms benign Not cancerous; often used for a growth that does not invade nearby tissue or spread distantly. Read definition → General Medical Terms acute Having a rapid onset, short course, or marked severity. Read definition → General Medical Terms gram A gram is a small metric unit of mass, widely used in clinical medicine to measure medication doses, body substances, and laboratory quantities. Read definition → General Medical Terms ICE ICE is a combination chemotherapy regimen used for certain lymphomas that have returned or resisted earlier lines of treatment. Read definition →
General Medical Terms benign Not cancerous; often used for a growth that does not invade nearby tissue or spread distantly. Read definition →
General Medical Terms acute Having a rapid onset, short course, or marked severity. Read definition →
General Medical Terms gram A gram is a small metric unit of mass, widely used in clinical medicine to measure medication doses, body substances, and laboratory quantities. Read definition →
General Medical Terms ICE ICE is a combination chemotherapy regimen used for certain lymphomas that have returned or resisted earlier lines of treatment. Read definition →