pyridoxine hydrochloride

Meaning of pyridoxine hydrochloride: Pyridoxine hydrochloride is a stable salt form of vitamin B6, converted in the body into an active coenzyme needed for amino acid metabolism.

Definition of pyridoxine hydrochloride

Pyridoxine hydrochloride is the hydrochloride salt form of pyridoxine, one of several related compounds collectively known as vitamin B6. This salt form is more stable for use in supplements and medications than pyridoxine on its own.

Once absorbed, pyridoxine is converted in the liver into pyridoxal 5 phosphate, the active coenzyme form of vitamin B6, which serves as an essential cofactor in numerous enzyme reactions involved in amino acid metabolism, including transamination and decarboxylation reactions that build and break down proteins and neurotransmitters.

Pyridoxal 5 phosphate is also required for glycogen breakdown and for the normal function of red blood cells, the nervous system, and the immune system. Pyridoxine hydrochloride is used as a dietary supplement to correct or prevent vitamin B6 deficiency and is included in certain combination medications, since some drugs can interfere with vitamin B6 levels or metabolism.

Used in a sentence

Pyridoxine hydrochloride was added to the regimen to help prevent a vitamin B6 deficiency.

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Good to know

Pyridoxine hydrochloride must be converted to its active coenzyme form, pyridoxal 5 phosphate, in the liver before it can participate in the enzyme reactions vitamin B6 is required for.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.