MedicalTerminology DB
Genetics & Molecular Biology Hormones, Diabetes & Metabolism

progesterone receptor negative

Meaning of progesterone receptor negative: Describes cells that do not have a protein to which the hormone progesterone will bind.

Definition of progesterone receptor negative

Describes cells that do not have a protein to which the hormone progesterone will bind. Cancer cells that are progesterone receptor negative do not need progesterone to grow, and usually do not stop growing when treated with hormones that block progesterone from binding. Also called PR-.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.