MedicalTerminology DB

Meaning of PF-00299804: A highly selective, orally bioavailabe small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity.

Definition of PF-00299804

A highly selective, orally bioavailabe small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity. PF-00299804 specifically and irreversibly binds to and inhibits human Her-1, Her-2, and Her-4, resulting in the proliferation inhibition and apoptosis of tumor cells that overexpress these receptors.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.