Home/Topics/General Medical Terms/penis General Medical Terms Reproductive, Pregnancy & Breast Health penis Listen Save Share Print Meaning of penis: An external male reproductive organ. Definition of penis An external male reproductive organ. It contains a tube called the urethra, which carries semen and urine to the outside of the body. Written and maintained by James Murray · Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations. Keep exploringRelated termsMore in General Medical Terms → Genetics & Molecular Biology PSA PSA is a protein measured in the blood that reflects prostate gland activity and can be elevated by cancer or noncancerous conditions. Read definition → Diseases & Disorders PCOS Despite the name, the defining problem is hormonal rather than the small follicles that scans pick up, and it reaches well beyond the ovaries. Read definition → Medications & Pharmacology DES A drug whose harms surfaced a generation later, in the children exposed before birth rather than in the women who were treated. Read definition → Diseases & Disorders erectile dysfunction Often the first visible sign of narrowed arteries elsewhere, which is why it is treated as a cardiovascular finding and not only a sexual one. Read definition →
Genetics & Molecular Biology PSA PSA is a protein measured in the blood that reflects prostate gland activity and can be elevated by cancer or noncancerous conditions. Read definition →
Diseases & Disorders PCOS Despite the name, the defining problem is hormonal rather than the small follicles that scans pick up, and it reaches well beyond the ovaries. Read definition →
Medications & Pharmacology DES A drug whose harms surfaced a generation later, in the children exposed before birth rather than in the women who were treated. Read definition →
Diseases & Disorders erectile dysfunction Often the first visible sign of narrowed arteries elsewhere, which is why it is treated as a cardiovascular finding and not only a sexual one. Read definition →