MedicalTerminology DB

Meaning of Down syndrome: A disorder caused by the presence of an extra chromosome 21 and characterized by intellectual disability and distinguishing physical features.

Definition of Down syndrome

A disorder caused by the presence of an extra chromosome 21 and characterized by intellectual disability and distinguishing physical features.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.