anti-EpCAM-Pseudomonas-exotoxin fusion protein

Definition / meaning of anti-EpCAM-Pseudomonas-exotoxin fusion protein

A substance being studied in the treatment of certain types of head and neck cancer. Anti-EpCAM-Pseudomonas-exotoxin fusion protein is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called Proxinium and VB4-845.

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The Web site of the National Cancer Institute (

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