Definition / meaning of 18F-MISO

A radioactive substance being studied as an imaging agent in head and neck cancers and other types of cancer. It binds to large molecules in tumor cells that have a low level of oxygen. Radiation given off by 18F-MISO is detected by a PET scan. The amount of 18F-MISO in the tumor may help decide the best treatment and help predict whether the cancer will come back after treatment. 18F-MISO is a type of radioimaging agent. Also called 18F-fluoromisonidazole and FMISO.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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