yttrium Y 90 monoclonal antibody Hu3S193

Definition / meaning of yttrium Y 90 monoclonal antibody Hu3S193

A radioimmunotherapeutic agent consisting of a humanized murine monoclonal antibody (hu3S193) directed against the tumor-associated Lewis Y epithelial antigen chelated to the radioisotope yttrium-90. Yttrium Y 90 monoclonal antibody Hu3S193 binds to Lewis Y epithelial antigen-expressing tumor cells, selectively delivering a cytotoxic dose of beta radiation.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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