A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon administration and after cellular uptake by skin or … [Read more...]
Search Results for: icd
ICD
A small device used to correct a heartbeat that is abnormal (too fast, too slow, or irregular). The device is placed by surgery in the chest or abdomen. Wires … [Read more...]
iCD40 receptor-expressing autologous dendritic cell vaccine BP-GMAX-CD1
A genetically-modified autologous dendritic cell-based vaccine expressing a drug-inducible costimulatory CD40 receptor (iCD40) with potential immunomodulating … [Read more...]
HER-2/neu intracellular domain protein
The cytoplasmic domain or intracellular domain (ICD) of the HER2/neu protein that exhibits tyrosine kinase activity. Based on sensitization theory, … [Read more...]
anti-DLL4 monoclonal antibody OMP-21M18
A humanized monoclonal antibody directed against the N-terminal epitope of Notch ligand DLL4 (delta-like 4) with potential antineoplastic activity. Anti-DLL4 … [Read more...]
implantable cardioverter-defibrillator
A small device used to correct a heartbeat that is abnormal (too fast, too slow, or irregular). The device is placed by surgery in the chest or abdomen. Wires … [Read more...]
dimerizer drug AP1903
A lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains … [Read more...]
dHER2+AS15 vaccine
A cancer vaccine consisting of a truncated recombinant HER2/neu peptide (dHER2) combined with the immunoadjuvant AS15 with potential immunostimulatory and … [Read more...]
anti-CEA IgCD28TCR-transduced autologous T cells
A population of autologous tumor infiltrating lymphocytes (TIL) transduced with a retroviral vector encoding the chimeric gene IgCD28TCR with potential … [Read more...]