A dipeptide boronic acid analogue with antineoplastic activity. Bortezomib reversibly inhibits the 26S proteasome, a large protease complex that degrades … [Read more...]
Search Results for: effect
dextroamphetamine-amphetamine
A combination of two synthetic agents with central nervous system stimulant activity. Both agents are non-catecholamine, sympathomimetic agents that elevate … [Read more...]
coenzyme Q10
A naturally occurring benzoquinone important in electron transport in mitochondrial membranes. Coenzyme-Q functions as an endogenous antioxidant; deficiencies … [Read more...]
Chk1 inhibitor SCH 900776
An agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 … [Read more...]
anti-interleukin 6 monoclonal antibody ALD518
A humanized monoclonal antibody directed against the pro-inflammatory cytokine interleukin-6 (Il-6) with potential immunomodulating activity. Upon … [Read more...]
antiperspirant cream F511
A cream formulation containing aluminum chlorohydrate with astringent and antiperspirant activities. Upon topical application of F511 cream, aluminium … [Read more...]
fulvestrant
A synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen … [Read more...]
doxorubicin prodrug INNO-206
A 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous … [Read more...]
carvedilol phosphate extended-release capsule
An extended-release capsule formulation containing the phosphate salt of carvedilol, a nonselective beta-adrenergic blocking agent with alpha 1-adrenergic … [Read more...]
anti-CD22 immunotoxin CAT-8015
A recombinant immunotoxin consisting of the Fv portion of the anti-CD22 antibody covalently fused to a 38 KDa fragment of Pseudomonas exotoxin-A (PE38) with … [Read more...]