A group of symptoms such as gas, bloating, abdominal pain, and diarrhea resulting from the body's inability to properly absorb nutrients. … [Read more...]
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Hsp90 inhibitor CNF2024
An orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 … [Read more...]
HIF-1alpha inhibitor PX-478
An orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be fully elucidated, HIF1-alpha inhibitor … [Read more...]
folate receptor-targeted technetium Tc 99m EC20
A folate receptor-targeting radiopharmaceutical consisting of a folate-containing tetrapeptide chelator to which technetium Tc 99m is linked. The folate … [Read more...]
ErbB-2 inhibitor ARRY-380
An orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. … [Read more...]
boronophenylalanine-fructose complex
A boronated phenylalanine complexed with fructose to increase its solubility. When exposed to neutron irradiation, boronophenylalanine absorbs neutrons and … [Read more...]
DNA plasmid vector pPRA-PSM vaccine
A cancer vaccine consisting of a DNA plasmid encoding epitopes of the human preferential antigen of melanoma (PRAME) and the prostate specific membrane antigen … [Read more...]
chlorozotocin
A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand … [Read more...]
3′-deoxy-3′-[18F]fluorothymidine
A radioconjugate consisting of a thymidine analogue radiolabeled with fluorine F 18, a positron emitting isotope. Phosphorylated by S-phase-specific thymidine … [Read more...]
autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine
A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, … [Read more...]