Search Results for: metastasis

bone metastasis

Cancer that has spread from the original (primary) tumor to the bone. … [Read more...]

bone marrow metastasis

Cancer that has spread from the original (primary) tumor to the bone marrow. … [Read more...]

distant metastasis

Refers to cancer that has spread from the original (primary) tumor to distant organs or distant lymph nodes. Also known as distant cancer. … [Read more...]

bone metastasis targeting peptide-11

A peptide that mimics naturally occurring interleukin-11 (IL-11) with interleukin receptor binding activity. Upon administration, bone metastasis targeting … [Read more...]

monoclonal antibody HeFi-1

A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on mitogen-activated … [Read more...]

prinomastat

A synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, … [Read more...]

MET tyrosine kinase inhibitor PF-04217903

An orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity. MET tyrosine kinase inhibitor PF-04217903 selectively … [Read more...]

marimastat

An orally-active synthetic hydroxamate with potential antineoplastic activity. Marimastat covalently binds to the zinc(II) ion in the active site of matrix … [Read more...]

PSP-94-derived peptide PCK3145

A synthetic 15-mer peptide corresponding to amino acids 31-45 of the 94-amino acid isoform of human prostate secretory protein (PSP-94) with potential … [Read more...]

Met tyrosine kinase inhibitor BMS-777607

An inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte … [Read more...]