A CD22-targeted cytotoxic immunoconjugate composed of a humanized IgG4 anti-CD22 antibody covalently linked to N-acetyl-gamma-calicheamicin dimethyl hydrazide … [Read more...]
Search Results for: double j
camptothecin-polymer conjugate IT-101
A formulation consisting of camptothecin conjugated to a hydrophilic, cyclodextrin-based linear polymer with potential antineoplastic activity. Upon intravenous … [Read more...]
polyglutamate camptothecin
A therapeutic formulation consisting of camptothecin, an alkaloid isolated from the Chinese tree Camptotheca acuminata, conjugated with polyglutamate. During … [Read more...]
anti-CD70 antibody-drug conjugate MDX-1203
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated … [Read more...]
gemtuzumab ozogamicin
A recombinant, humanized anti-CD33 monoclonal antibody attached to the cytotoxic antitumor antibiotic calicheamicin. In this conjugate, the antibody binds to … [Read more...]
BAY 56-3722
A water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA … [Read more...]
polyethyleneglycol-7-ethyl-10-hydroxycamptothecin
A polyethylene glycol (PEG) conjugate of 7-ethyl-10-hydroxycamptothecin with potential antineoplastic activity. After hydrolysis in vivo, … [Read more...]
indium In 111-CMD-193
A radiolabeled antibody-targeted antineoplastic antibiotic consisting of the enediyne antibiotic calicheamicin conjugated with anti-Lewis Y antibody and labeled … [Read more...]