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p38 / Tie2 kinase inhibitor Arry-614

An orally bioavailable small-molecule inhibitor of p38 and Tie2 kinases with potential antineoplastic, anti-inflammatory and antiangiogenic activities. p38/Tie2 … [Read more...]

Pim kinase inhibitor SGI-1776

A small-molecule pan-Pim protein kinase inhibitor with potential antineoplastic activity. Pim kinase inhibitor SGI-1776 binds to and inhibits the activities of … [Read more...]

NMPRTase inhibitor APO866

A small molecule with potential antineoplastic and antiangiogenic activities. NMPRTase inhibitor APO866 binds to and inhibits nicotinamide … [Read more...]

mTOR kinase inhibitor AZD8055

An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine … [Read more...]

montelukast sodium

The orally bioavailable monosodium salt of montelukast, a selective cysteinyl leukotriene receptor antagonist with anti-inflammatory and bronchodilating … [Read more...]

NY-ESO-1 plasmid DNA cancer vaccine

A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1 with potential immunostimulating and antitumor activities. Upon … [Read more...]

pravastatin

The sodium salt of pravastatin with cholesterol-lowering and potential antineoplastic activities. Pravastatin competitively inhibits hepatic … [Read more...]

PEGASYS

(Other name for: PEG-interferon alfa-2a) … [Read more...]

multitargeted tyrosine kinase inhibitor BIBF 1120

An orally bioavailable, indolinone-derived, receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Multitargeted … [Read more...]

pyruvate kinase inhibitor TLN-232

A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may … [Read more...]