A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. Tanespimycin helps cause the breakdown of certain … [Read more...]
Search Results for: -al
O6-benzylguanine
A guanine analogue with antineoplastic activity. O(6)-benzylguanine binds the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase (AGT), transferring the … [Read more...]
laromustine
A sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE … [Read more...]
isavuconazole
A water-soluble triazole prodrug with broad-spectrum antifungal activity. Administered intravenously or orally with high oral bioavailability, isavuconazole is … [Read more...]
anti-A5B1 integrin monoclonal antibody PF-04605412
A monoclonal antibody directed against the human alpha5beta1 integrin with potential antiangiogenic and antineoplastic activities. Anti-alpha5beta1 integrin … [Read more...]
human anti-alpha-v integrin monoclonal antibody
A pan alpha-v human monoclonal antibody that recognizes alpha-v beta-1, alpha-v beta-3, alpha-v beta-5, and alpha-v beta-6 integrins with antiangiogenic and … [Read more...]
cytomegalovirus pp65-specific cytotoxic T lymphocytes
Cytotoxic T lymphocytes (CTLs) specifically reactive to the cytomegalovirus (CMV) phosphoprotein pp65 with potential antiviral activity. To prepare CMV … [Read more...]
autologous NSCLC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine
A vaccine consisting of irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous non-small cell lung cancer … [Read more...]
alpha-Gal glycosphingolipids
A preparation of glycosphingolipids (GSL), containing the disaccharide epitope galactose-alpha-1,3-galactose (alpha-Gal), with potential antineoplastic … [Read more...]
alpha-1,3-galactosyltransferase-expressing allogeneic lung tumor cell vaccine
An allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived from allogeneic lung tumor cells, … [Read more...]