Search Results for: -a

yttrium Y 90 monoclonal antibody BrE-3

A radioimmunotherapeutic agent consisting of a monoclonal antibody (BrE-3) directed against the tumor-associated antigen epithelial glycoprotein mucin chelated … [Read more...]

AVR118

A peptide-nucleic acid immunomodulator with proinflammatory, broad-spectrum antiviral, and potential antineoplastic activities. AVR118 stimulates the peripheral … [Read more...]

asparaginase-Erwinia

An enzyme isolated from the bacterium Erwinia chrysanthemi (E. carotovora). Asparagine is critical to protein synthesis in leukemic cells, which cannot … [Read more...]

androstane steroid HE3235

An orally bioavailable adrenal steroid analogue with potential antineoplastic activity. Androstane steroid HE3235 appears to bind the androgen receptor (AR), … [Read more...]

alpha-type-1 polarized dendritic cells

A population of mature polarized dendritic cells with potent immunostimulating activity. Treating bone marrowed-derived dendritic cells (DCs) with … [Read more...]

PR-104

A non-toxic, small-molecule, hypoxia-activated, 3,5-dinitrobenzamide nitrogen mustard pre-prodrug with potential antitumor activity. Upon intravenous … [Read more...]

HLA-A*0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine

A cancer vaccine containing three HLA-A*2402-restricted peptide epitopes with potential immunostimulatory, antiangiogenic, and antitumor activities. Vaccine … [Read more...]

fluphenazine hydrochloride

The hydrochloride salt of fluphenazine, a phenothiazine with antipsychotic activity and potential antineoplastic activity. Fluphenazine blocks postsynaptic … [Read more...]

BRAF(V600E) kinase inhibitor RO5185426

An orally bioavailable, ATP-competitive, small-molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. BRAF(V600E) kinase inhibitor … [Read more...]

baclofen

A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B … [Read more...]